Description

2-((3-Allyl-4-Oxo-3,4,5,6,7,8-Hexahydrobenzo[4,5]Thieno[2,3-D]Pyrimidin-2-Yl)Thio)-n-(3-Chlorophenyl)Acetamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a sophisticated heterocyclic scaffold for creating novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting oncology, neurology, and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel small-molecule drug candidates, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the biological activity and pharmacokinetic properties of lead compounds.
• API Development: Integral in the process development and scale-up of complex Active Pharmaceutical Ingredients (APIs) for preclinical and clinical trials.
• Chemical Biology Probes: Employed in the development of chemical probes for studying biological mechanisms and target validation in disease models.
• Custom Synthesis: Available for contract research organizations (CROs) and CDMOs requiring bespoke, high-complexity intermediates for client projects.

Basic Information

Product Name	2-((3-Allyl-4-Oxo-3,4,5,6,7,8-Hexahydrobenzo[4,5]Thieno[2,3-D]Pyrimidin-2-Yl)Thio)-n-(3-Chlorophenyl)Acetamide
CAS No.	421577-85-7
Molecular Formula	C21H20ClN3O2S2
Molecular Weight	453.98 g/mol
Synonyms	2-[(3-Allyl-4-oxo-5,6,7,8-tetrahydro-3H-benzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio]-N-(3-chlorophenyl)acetamide; 421577-85-7; N-(3-Chlorophenyl)-2-[[3-(2-propen-1-yl)-4-oxo-5,6,7,8-tetrahydro-3H-benzo[4,5]thieno[2,3-d]pyrimidin-2-yl]thio]acetamide; 2-((3-Allyl-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)-N-(3-chlorophenyl)acetamide; Tetrahydrobenzothienopyrimidine derivative
EINECS	Contact for details

Quality Control

Our 2-((3-Allyl-4-Oxo-3,4,5,6,7,8-Hexahydrobenzo[4,5]Thieno[2,3-D]Pyrimidin-2-Yl)Thio)-n-(3-Chlorophenyl)Acetamide is manufactured under strict quality management systems. All batches undergo rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with research-grade and pharmaceutical intermediate standards. Comprehensive Certificates of Analysis (COA) detailing purity, impurities, and full characterization data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound may be light-sensitive (store away from light) and hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.