Description

4-Bromo-2-Fluoro-5-Methylaniline is a high-purity halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which allows for selective functionalization and the introduction of both bromine and fluorine atoms into complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring halogenated aromatic motifs for bioactivity.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine and bromine atoms enhance metabolic stability and binding affinity.
• Material Science Research: Employed in the creation of organic electronic materials, liquid crystals, and specialty polymers.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing complex, halogenated dyes and pigments.
• Cross-Coupling Reactions: Serves as a versatile substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry in exploring new synthetic pathways.

Basic Information

Product Name	4-Bromo-2-Fluoro-5-Methylaniline
CAS No.	418762-26-2
Molecular Formula	C7H7BrFN
Molecular Weight	204.04 g/mol
Synonyms	2-Fluoro-4-bromo-5-methylaniline; 5-Amino-2-bromo-4-fluorotoluene; 4-Bromo-2-fluoro-5-methylbenzenamine; 2-Bromo-4-fluoro-5-aminotoluene; Benzenamine, 4-bromo-2-fluoro-5-methyl-; 5-Methyl-4-bromo-2-fluoroaniline; 4-Bromo-2-fluoro-5-methyl-phenylamine
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluoro-5-Methylaniline is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We adhere to cGMP standards where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.