Description

Ethyl 7-Oxo-2-(trifluoromethyl)-3,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate is a high-value, heterocyclic organic compound featuring a fused triazolopyrimidine core with a trifluoromethyl group and an ester functionality. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate (API) for the synthesis of novel active ingredients. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in developing new therapeutic agents, particularly in areas requiring fluorinated bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-inflammatory applications, and anti-infective agents.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Chemical Biology & Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and high-throughput screening libraries to identify new bioactive compounds.
• Fluorinated Compound Synthesis: An essential precursor for introducing the triazolopyrimidine moiety into more complex fluorinated molecules for material science and specialty chemical applications.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical and agrochemical industries.

Basic Information

Product Name	Ethyl 7-Oxo-2-(trifluoromethyl)-3,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate
CAS No.	414899-89-1
Molecular Formula	C9H7F3N4O3
Molecular Weight	276.18 g/mol
Synonyms	Ethyl 2-(trifluoromethyl)-7-oxo-3,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate; 6-Carbethoxy-2-trifluoromethyl-5,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidin-7-one; 2-Trifluoromethyl-7-oxo-6-ethoxycarbonyl-5,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidine; [1,2,4]Triazolo[1,5-a]pyrimidine-6-carboxylic acid, 3,7-dihydro-7-oxo-2-(trifluoromethyl)-, ethyl ester; CAS 414899-89-1
EINECS	Contact for details

Quality Control

Our production of Ethyl 7-Oxo-2-(trifluoromethyl)-3,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate adheres to stringent ISO 9001 quality management principles. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.