Description

Methyl 4-((6-(3,5-Dimethyl-1H-Pyrazol-1-Yl)Pyrimidin-4-Yl)Oxy)Benzoate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is valued for its precise molecular architecture, which serves as a critical building block in modern medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within oncology and targeted therapy research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates, especially kinase inhibitors.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Oncology Research: Serves as a core scaffold for developing targeted cancer therapies due to its pyrimidine and pyrazole motifs.
• Chemical Synthesis: Employed in organic synthesis for constructing complex heterocyclic systems.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of APIs.

Basic Information

Item	Detail
Product Name	Methyl 4-((6-(3,5-Dimethyl-1H-Pyrazol-1-Yl)Pyrimidin-4-Yl)Oxy)Benzoate
CAS No.	413620-32-3
Molecular Formula	C17H16N4O3
Molecular Weight	324.34 g/mol
Synonyms	Methyl 4-[(6-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidin-4-yl)oxy]benzoate; 4-((6-(3,5-Dimethyl-1H-pyrazol-1-yl)pyrimidin-4-yl)oxy)benzoic acid methyl ester; Benzoic acid, 4-((6-(3,5-dimethyl-1H-pyrazol-1-yl)-4-pyrimidinyl)oxy)-, methyl ester; CAS 413620-32-3
EINECS	Contact for details

Quality Control

Our Methyl 4-((6-(3,5-Dimethyl-1H-Pyrazol-1-Yl)Pyrimidin-4-Yl)Oxy)Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.