Description

4-[4-(Trifluoromethyl)Phenyl]Benzylamine Hydrochloride is a high-purity organic intermediate featuring a benzylamine core substituted with a trifluoromethylphenyl group. This compound is valued for its role as a critical building block in the synthesis of advanced pharmaceutical agents and agrochemicals, where the trifluoromethyl group is known to enhance metabolic stability and bioavailability. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Serves as a building block for developing new herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl moiety.
• Ligand and Catalyst Development: Used in organic and medicinal chemistry research to create novel ligands for catalysis or as a scaffold for molecular probes.
• Material Science Research: Potential monomer or additive in the development of advanced polymers and functional materials with specific optical or electronic properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales.

Basic Information

Product Name	4-[4-(Trifluoromethyl)Phenyl]Benzylamine Hydrochloride
CAS No.	412950-48-2
Molecular Formula	C14H12F3N • HCl
Molecular Weight	287.71 g/mol
Synonyms	4-[4-(Trifluoromethyl)phenyl]benzenemethanamine hydrochloride; [4-(4-Trifluoromethylphenyl)phenyl]methanamine hydrochloride; 1-[4-(Trifluoromethyl)phenyl]-4-(aminomethyl)benzene hydrochloride; α-(4-(4-(Trifluoromethyl)phenyl)phenyl)methanamine hydrochloride; (4'-(Trifluoromethyl)biphenyl-4-yl)methanamine hydrochloride; 4-(4-Trifluoromethylphenyl)benzylamine HCl; 4-(α-Aminobenzyl)-α,α,α-trifluorotoluene hydrochloride
EINECS	Contact for details

Quality Control

Our 4-[4-(Trifluoromethyl)Phenyl]Benzylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets stringent specifications for research and development use. A Certificate of Analysis (COA) documenting all test results is provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.