Description

2-(Piperidin-4-Yloxy)-Pyrimidine Hydrochloride is a high-purity (98+%) organic salt with the molecular formula C9H14ClN3O and a molecular weight of 215.68. This compound serves as a critical pharmaceutical intermediate and building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its piperidine-pyrimidine scaffold.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel herbicides or fungicides.
• Chemical Biology Probe Synthesis: Utilized for creating tool compounds to study biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A starting material for the custom production of complex organic molecules for clients.
• Academic Research: Employed in university and institutional labs for methodological development and novel heterocyclic chemistry.

Basic Information

Product Name	2-(Piperidin-4-Yloxy)-Pyrimidine Hydrochloride
CAS No.	412293-92-6
Molecular Formula	C9H14ClN3O
Molecular Weight	215.68 g/mol
Synonyms	4-[(Pyrimidin-2-yl)oxy]piperidine hydrochloride; 2-(4-Piperidyloxy)pyrimidine hydrochloride; Pyrimidine, 2-(4-piperidinyloxy)-, hydrochloride; 2-Piperidin-4-yloxy-pyrimidine HCl; 412293-92-6; 2-(Piperidin-4-yloxy)pyrimidine HCl; 4-(2-Pyrimidinyloxy)piperidine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 2-(Piperidin-4-Yloxy)-Pyrimidine Hydrochloride is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure it meets our high-purity standards (98+% minimum). Our quality assurance protocols are designed to provide consistency and reliability for your critical R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.