Description

5-Pyrimidinecarbonitrile, 4-Amino-2-(Hydroxymethyl)- (9Ci) is a high-purity, functionalized pyrimidine derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of novel pharmaceutical intermediates and active ingredients. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for constructing complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of nucleoside analogs, kinase inhibitors, and other small molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive pyrimidine core.
• Fine Chemical Synthesis: Serves as a versatile scaffold for constructing complex molecules in custom synthesis and process development for specialty chemicals.
• Bioconjugation & Probe Development: The reactive nitrile and hydroxyl groups enable its use in creating labeled compounds and molecular probes for biochemical research.
• Material Science Precursor: Potential use in the synthesis of organic ligands for metal-organic frameworks (MOFs) or functional polymers.

Basic Information

Product Name	5-Pyrimidinecarbonitrile, 4-Amino-2-(Hydroxymethyl)- (9Ci)
CAS No.	412277-96-4
Molecular Formula	C6H6N4O
Molecular Weight	150.14 g/mol
Synonyms	4-Amino-2-(hydroxymethyl)pyrimidine-5-carbonitrile; 2-(Hydroxymethyl)-4-aminopyrimidine-5-carbonitrile; 4-Amino-2-(hydroxymethyl)-5-pyrimidinecarbonitrile; 4-Amino-2-hydroxymethyl-5-cyanopyrimidine; 5-Cyano-4-amino-2-hydroxymethylpyrimidine
EINECS	Contact for details

Quality Control

Our 5-Pyrimidinecarbonitrile, 4-Amino-2-(Hydroxymethyl)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.