Description

3-(tert-Butylcarbamoyl)Benzene-1-Sulfonyl Chloride is a high-purity sulfonyl chloride derivative, a key synthetic intermediate in advanced organic chemistry. Its value lies in its dual functional groups, enabling precise and efficient construction of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel sulfonamide-based compounds.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs containing sulfonamide pharmacophores.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that utilize sulfonyl-based chemistry.
• Chemical Biology & Proteomics: Serves as a reactive handle for chemical probes and activity-based protein profiling (ABPP) reagents targeting specific enzymes.
• Polymer Chemistry: Employed as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of specialized sulfonated dyes and colorants.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving diverse R&D projects.

Basic Information

Product Name	3-(tert-Butylcarbamoyl)Benzene-1-Sulfonyl Chloride
CAS No.	409109-00-8
Molecular Formula	C11H14ClNO3S
Molecular Weight	275.75 g/mol
Synonyms	3-[(tert-Butylcarbamoyl)]benzenesulfonyl chloride; 3-(tert-Butylaminocarbonyl)benzenesulfonyl chloride; 3-(N-tert-Butylcarbamoyl)benzenesulfonyl chloride; m-(tert-Butylcarbamoyl)benzenesulfonyl chloride; Benzenesulfonyl chloride, 3-[(1,1-dimethylethyl)amino]carbonyl]-; 3-(tert-Butylcarbamoyl)phenylsulfonyl chloride; 3-(N-tert-Butylureido)benzenesulfonyl chloride (common misnomer); TBCBS-Cl
EINECS	Contact for details

Quality Control

Our 3-(tert-Butylcarbamoyl)Benzene-1-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.