Description

2-Chloro-5-Nitro-4,6-Pyrimidinediamine is a high-purity, functionalized pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its unique halogenated and nitrated diaminopyrimidine structure makes it an indispensable intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of nucleoside analogs, kinase inhibitors, and other heterocyclic APIs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Dye & Pigment Industry: Potential intermediate for the production of specialized colorants and photographic chemicals.
• Material Science: Building block for creating novel organic electronic materials and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Chloro-5-Nitro-4,6-Pyrimidinediamine
CAS No.	408352-74-9
Molecular Formula	C4H5ClN6O2
Molecular Weight	204.57 g/mol
Synonyms	4,6-Diamino-2-chloro-5-nitropyrimidine; 2-Chloro-5-nitropyrimidine-4,6-diamine; 5-Nitro-2-chloropyrimidine-4,6-diamine; 2-Chloro-5-nitro-4,6-pyrimidinediyldiamine; 2-Chloro-5-nitro-4,6-diaminopyrimidine; 4,6-Diamino-2-chloro-5-nitro-pyrimidine; 2-Chloro-5-nitro-4,6-pyrimidinediamine
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Nitro-4,6-Pyrimidinediamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and residual solvents. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.