Description

4-Methoxy-L-Tryptophan is a specialized, non-proteinogenic amino acid derivative featuring a methoxy substituent on the indole ring. This structural modification is of significant interest for its role as a key synthetic intermediate and building block in advanced pharmaceutical research and development. It is primarily utilized by research institutions and manufacturers in the life sciences sector for the synthesis of novel bioactive compounds, including potential drug candidates and biochemical probes.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex molecules for drug discovery programs, particularly those targeting neurological and metabolic pathways.
• Biochemical Research: Used as a building block for creating labeled analogs, peptide modifications, and enzyme substrates to study biological processes.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.
• Peptide Synthesis: Incorporated into custom peptides to introduce specific structural features or to study structure-activity relationships (SAR).
• Metabolite Synthesis: Utilized in the preparation of metabolites for pharmacokinetic and toxicological studies during drug development.

Basic Information

Product Name	4-Methoxy-L-Tryptophan
CAS No.	406938-53-2
Molecular Formula	C12H14N2O3
Molecular Weight	234.25 g/mol
Synonyms	(S)-2-Amino-3-(4-methoxy-1H-indol-3-yl)propanoic acid; L-4-Methoxytryptophan; 4-Methoxy-L-Trp; 4-MeO-L-Trp; 4-Methoxy-L-α-amino-1H-indole-3-propanoic acid; 4-Methoxytryptophan, L-; 4-Methoxyindole-3-alanine
EINECS	Contact for details

Quality Control

Our 4-Methoxy-L-Tryptophan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity verification, to ensure it meets the stringent requirements of research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-Isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.