Description

5-Pyrimidinecarboxylicacid,4-(2,6-Difluorophenyl)-1,2,3,4-Tetrahydro-6-Methyl-2-Oxo-,Ethylester(9Ci) CAS NO 406468-02-8 is a high-purity, synthetically valuable pyrimidine derivative. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily required by R&D and production teams in the pharmaceutical and agrochemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Medicinal Chemistry Research: A versatile scaffold for structure-activity relationship (SAR) studies and library synthesis due to its substituted pyrimidine core.
• Agrochemical Development: Building block for creating new active ingredients in crop protection products, such as fungicides or herbicides.
• Chemical Synthesis: Used in organic synthesis for constructing complex heterocyclic compounds and fine chemicals.
• Biochemical Research: Potential tool compound for studying enzymatic processes and biological pathways involving pyrimidine recognition.

Basic Information

Item	Details
Product Name	5-Pyrimidinecarboxylicacid,4-(2,6-Difluorophenyl)-1,2,3,4-Tetrahydro-6-Methyl-2-Oxo-,Ethylester(9Ci)
CAS No.	406468-02-8
Molecular Formula	C15H16F2N2O3
Molecular Weight	310.30 g/mol
Synonyms	4-(2,6-Difluorophenyl)-1,2,3,4-tetrahydro-6-methyl-2-oxo-5-pyrimidinecarboxylic acid ethyl ester; Ethyl 4-(2,6-difluorophenyl)-1,2,3,4-tetrahydro-6-methyl-2-oxopyrimidine-5-carboxylate; 406468-02-8; 5-Pyrimidinecarboxylic acid, 4-(2,6-difluorophenyl)-1,2,3,4-tetrahydro-6-methyl-2-oxo-, ethyl ester; Ethyl 4-(2,6-difluorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all critical specifications. We support development and scale-up with custom purity grades and regulatory documentation as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.