Description

Butanoic Acid, 3-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-4-(Phenylthio)-, 1,1-Dimethylethyl Ester, (3R)- is a high-purity, chiral amino acid derivative featuring a tert-butyl ester and a fluorenylmethyloxycarbonyl (Fmoc) protecting group. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled introduction of specific amino acid sequences. It is primarily required by pharmaceutical R&D and biotechnology organizations for the development of novel therapeutic peptides and peptidomimetics.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a protected, activated amino acid derivative for the automated synthesis of complex peptides.
• Pharmaceutical Research: A key intermediate in the discovery and development of peptide-based drugs targeting various diseases.
• Bioconjugation: Used to introduce specific functional groups or linkers onto peptides for drug delivery systems or diagnostic probes.
• Chemical Biology: Employed in the synthesis of peptide libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Academic Research: A reagent for studying peptide structure, function, and synthesis methodologies in university and institutional labs.

Basic Information

Product Name	Butanoic Acid, 3-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-4-(Phenylthio)-, 1,1-Dimethylethyl Ester, (3R)-
CAS No.	406233-30-5
Molecular Formula	C29H31NO4S
Molecular Weight	489.63 g/mol
Synonyms	Fmoc-Cys(SPh)-OtBu; Fmoc-S-phenyl-L-cysteine tert-butyl ester; (3R)-3-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-4-(phenylthio)butanoic acid 1,1-dimethylethyl ester; N-α-Fmoc-S-phenyl-L-cysteine tert-butyl ester; Fmoc-L-Cys(SPh)-OtBu; Fmoc-Cys(S-Ph)-OtBu; Fmoc-S-phenylcysteine t-butyl ester; N-Fmoc-S-phenyl-L-cysteine t-butyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data, including HPLC, NMR, and MS, to guarantee identity, purity, and chiral integrity. Certificates of Analysis (COA) are available upon request. Our quality management system supports the needs of research and development under cGMP-like controls where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere or in a desiccator to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.