Description

2(1H)-Pyrimidinone,5-Acetyl-4-(2-Fluorophenyl)-3,4-Dihydro-6-Methyl-(9Ci) is a high-purity, fluorinated dihydropyrimidinone derivative, a key structural motif in medicinal chemistry. This compound is valued for its role as a versatile synthetic intermediate in the development of novel active pharmaceutical ingredients (APIs). It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for lead optimization and process chemistry. The product is supplied with full analytical documentation to ensure batch-to-batch consistency for critical applications.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing potential drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Research: Used in the discovery and development of new herbicides and fungicides, leveraging its heterocyclic core structure.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of diverse chemical libraries for high-throughput screening.
• Academic & Contract Research: Employed in universities and CROs (Contract Research Organizations) for methodological studies and the exploration of new synthetic pathways.
• Material Science Exploration: Investigated as a potential monomer or additive for creating specialty polymers with unique properties.

Basic Information

Product Name	2(1H)-Pyrimidinone,5-Acetyl-4-(2-Fluorophenyl)-3,4-Dihydro-6-Methyl-(9Ci)
CAS No.	405154-00-9
Molecular Formula	C₁₃H₁₃FN₂O₂
Molecular Weight	248.26 g/mol
Synonyms	5-Acetyl-4-(2-fluorophenyl)-3,4-dihydro-6-methyl-2(1H)-pyrimidinone; 4-(2-Fluorophenyl)-5-acetyl-3,4-dihydro-6-methylpyrimidin-2(1H)-one; 5-Acetyl-4-(2-fluorophenyl)-6-methyl-3,4-dihydropyrimidin-2(1H)-one; 405154-00-9; SCHEMBL18804279; AKOS025147329; ZINC000004098756; A1-00826.
EINECS	Contact for details

Quality Control

Every batch of our 2(1H)-Pyrimidinone,5-Acetyl-4-(2-Fluorophenyl)-3,4-Dihydro-6-Methyl-(9Ci) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.