Description

S-(2-Thiazolyl)-L-Cysteine is a specialized, non-proteinogenic amino acid derivative that serves as a critical building block in advanced chemical synthesis. This compound is valued for its unique thiazole moiety, which introduces heterocyclic functionality essential for modulating biological activity and material properties. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, biochemical probes, and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition or acting as prodrugs.
• Biochemical Research: Used in peptide synthesis to incorporate a thiazole heterocycle, studying protein structure-function relationships and enzyme-substrate interactions.
• Proteomics & Labeling Reagents: Serves as a component in creating affinity tags or fluorescent probes for protein labeling and detection.
• Chemical Biology Tool: Employed to develop activity-based probes for profiling cysteine proteases or other thiol-reactive enzymes.
• Fine Chemical Synthesis: Acts as a chiral synthon for constructing complex molecules in asymmetric synthesis for agrochemicals or advanced materials.
• Reference Standard: Supplied as a high-purity compound for analytical method development and quality control in regulatory environments.

Basic Information

Product Name	S-(2-Thiazolyl)-L-Cysteine
CAS No.	405150-20-1
Molecular Formula	C6H8N2O2S2
Molecular Weight	204.27 g/mol
Synonyms	L-Cysteine, S-(2-thiazolyl)-; (2R)-2-Amino-3-[(1,3-thiazol-2-yl)sulfanyl]propanoic acid; 2-Thiazolyl-L-cysteine; S-2-Thiazolylcysteine; (R)-2-Amino-3-((thiazol-2-yl)thio)propanoic acid; NSC 760466; Thiazolylcysteine
EINECS	Contact for details

Quality Control

Our S-(2-Thiazolyl)-L-Cysteine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm enantiomeric integrity, and spectroscopic identification (IR, NMR). We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment, ensuring compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.