Description

n-Methyl-1-(pyrimidin-2-yl)piperidin-4-amine is a high-purity, nitrogen-containing heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research and development chemists, process development teams, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor research and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Development: Potential precursor for creating novel ligands in coordination chemistry and catalysis.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	n-Methyl-1-(pyrimidin-2-yl)piperidin-4-amine
CAS No.	405058-10-8
Molecular Formula	C10H16N4
Molecular Weight	192.26 g/mol
Synonyms	1-Methyl-4-(pyrimidin-2-ylamino)piperidine; 4-Amino-1-methyl-N-(pyrimidin-2-yl)piperidine; 1-Methyl-1-(2-pyrimidinyl)-4-piperidinamine; N-Methyl-1-(2-pyrimidinyl)-4-piperidinamine; 405058-10-8; 1-Methyl-4-(pyrimidin-2-ylamino)piperidine; 4-(Pyrimidin-2-ylamino)-1-methylpiperidine
EINECS	Contact for details

Quality Control

Our n-Methyl-1-(pyrimidin-2-yl)piperidin-4-amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and production applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.