Description

4-(3-Chloro-4-Fluorophenyl)Aniline is a high-purity, halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which introduces both chloro and fluoro substituents onto the phenyl ring, enabling precise modifications in target molecules. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of modern herbicides and fungicides, where the chloro-fluoro substitution pattern enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a starting material for synthesizing specialized aromatic amines used in electronic display technologies.
• Polymer Chemistry: Acts as a monomer or chain modifier in the production of high-performance polymers, such as polyimides and aramids.
• Dye & Pigment Manufacturing: Utilized in the creation of complex, halogenated dyes that offer superior lightfastness and color properties.
• Research & Development: Employed in academic and industrial R&D labs for method development and exploring new chemical entities in medicinal chemistry.

Basic Information

Product Name	4-(3-Chloro-4-Fluorophenyl)Aniline
CAS No.	405058-02-8
Molecular Formula	C12H9ClFN
Molecular Weight	221.66 g/mol
Synonyms	4-Amino-2-chloro-1-fluorobenzene; 3-Chloro-4-fluoroaniline; 2-Chloro-4-aminobenzene; 1-Amino-3-chloro-4-fluorobenzene; 4-(3-Chloro-4-fluorophenyl)benzenamine; Benzenamine, 3-chloro-4-fluoro-; (3-Chloro-4-fluorophenyl)amine
EINECS	Contact for details

Quality Control

Our 4-(3-Chloro-4-Fluorophenyl)Aniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging until use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.