Description

4-Chloromethyl-n-[4-Methyl-3-[[4-(Pyridin-3-Yl)Pyrimidin-2-Yl]Amino]Phenyl]Benzamide CAS NO 404844-11-7 is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value in medicinal chemistry for the research and development of targeted small-molecule therapeutics. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel kinase inhibitors and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of investigational drug candidates, particularly those targeting specific kinase pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes for new therapeutic agents.
• Biochemical Tool Compound: Serves as a precursor for developing labeled probes or active pharmaceutical ingredients (APIs) for biological testing.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of complex organic molecules for clinical trials.
• Academic Research: Utilized in university and institutional labs for cutting-edge research in organic synthesis and drug discovery.

Basic Information

Product Name	4-Chloromethyl-n-[4-Methyl-3-[[4-(Pyridin-3-Yl)Pyrimidin-2-Yl]Amino]Phenyl]Benzamide
CAS No.	404844-11-7
Molecular Formula	C25H22ClN5O
Molecular Weight	443.93 g/mol
Synonyms	4-Chloromethyl-N-[4-methyl-3-({4-(pyridin-3-yl)pyrimidin-2-yl}amino)phenyl]benzamide; 404844-11-7; Benzamide, 4-(chloromethyl)-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-; UNII-7Q6I7Q0L8I; 7Q6I7Q0L8I; 4-(Chloromethyl)-N-[4-methyl-3-({4-(pyridin-3-yl)pyrimidin-2-yl}amino)phenyl]benzamide; N-[4-Methyl-3-({4-(pyridin-3-yl)pyrimidin-2-yl}amino)phenyl]-4-(chloromethyl)benzamide
EINECS	Contact for details

Quality Control

Every batch of this high-value intermediate is produced and tested under strict quality management systems. We provide comprehensive analytical data to support your research and regulatory needs. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are supplied with each shipment, ensuring traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.