Description

3-(4-Methoxyphenyl)-2,2-Dimethyl-2,3-Dihydroquinazolin-4(1H)-One is a high-value, synthetically derived quinazolinone derivative, serving as a critical advanced intermediate in modern organic synthesis. Its unique fused heterocyclic structure makes it a versatile building block for constructing complex molecules with potential biological activity. This compound is primarily sought after by research institutions and pharmaceutical development companies engaged in medicinal chemistry and drug discovery programs. Its reliable synthesis and consistent quality are paramount for downstream application success.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Medicinal Chemistry Research: Used as a core scaffold or a functionalized intermediate for structure-activity relationship (SAR) studies and library synthesis in academic and industrial R&D labs.
• Agrochemical Development: Acts as a building block for creating new active ingredients in crop protection agents, leveraging its heterocyclic framework.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme function or protein-protein interactions within biological systems.
• Material Science Research: Investigated as a potential monomer or additive for creating specialty polymers with specific optical or electronic properties.

Basic Information

Item	Details
Product Name	3-(4-Methoxyphenyl)-2,2-Dimethyl-2,3-Dihydroquinazolin-4(1H)-One
CAS No.	404835-88-7
Molecular Formula	C₁₇H₁₈N₂O₂
Molecular Weight	282.34 g/mol
Synonyms	2,2-Dimethyl-3-(4-methoxyphenyl)-2,3-dihydro-1H-quinazolin-4-one; 3-(4-Methoxyphenyl)-2,2-dimethyl-1,2,3,4-tetrahydroquinazolin-4-one; 4(1H)-Quinazolinone, 2,3-dihydro-3-(4-methoxyphenyl)-2,2-dimethyl-; 404835-88-7; Quinazolinone derivative CAS 404835-88-7
EINECS	Contact for details

Quality Control

Our production of 3-(4-Methoxyphenyl)-2,2-Dimethyl-2,3-Dihydroquinazolin-4(1H)-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for research and development applications. All material is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We are committed to meeting the exacting standards required for pharmaceutical intermediates and advanced synthetic chemistry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.