Description

3-Fluoro-4-[2-(4-Morpholinyl)Ethoxy]Phenylamine is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular architecture combining a fluorinated phenyl ring with a morpholine-ethoxy linker. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research and development. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers engaged in creating next-generation therapeutics for oncology and other disease areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of targeted kinase inhibitors and other small molecule drugs.
• Chemical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Synthesis: Serves as a precursor for developing novel crop protection agents with enhanced activity.
• Material Science: Potential monomer or additive for specialty polymers and advanced functional materials.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	3-Fluoro-4-[2-(4-Morpholinyl)Ethoxy]Phenylamine
CAS No.	403741-00-4
Molecular Formula	C12H17FN2O2
Molecular Weight	240.28 g/mol
Synonyms	3-Fluoro-4-(2-morpholinoethoxy)aniline; 4-(2-(3-Fluoro-4-aminophenoxy)ethyl)morpholine; 3-Fluoro-4-(2-morpholin-4-ylethoxy)benzenamine; 403741-00-4; 4-(2-(3-Fluoro-4-aminophenoxy)ethyl)morpholine; Benzenamine, 3-fluoro-4-[2-(4-morpholinyl)ethoxy]-
EINECS	Contact for details

Quality Control

Our production of 3-Fluoro-4-[2-(4-Morpholinyl)Ethoxy]Phenylamine adheres to stringent quality management protocols. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality system is designed to support cGMP (current Good Manufacturing Practice) requirements for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.