Description

5-(4-Chlorobenzyl)-1H-Pyrazolo[3,4-D]Pyrimidin-4(5H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyrimidine class of heterocyclic compounds. This compound serves as a critical building block in medicinal chemistry, enabling the synthesis of targeted therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly kinase inhibitors.
• Biochemical Research: Used as a reference standard or tool compound in enzymatic assays and target validation studies.
• Organic Synthesis: Serves as a versatile precursor for constructing complex heterocyclic scaffolds with potential biological activity.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	5-(4-Chlorobenzyl)-1H-Pyrazolo[3,4-D]Pyrimidin-4(5H)-One
CAS No.	402570-41-6
Molecular Formula	C₁₂H₉ClN₄O
Molecular Weight	260.68 g/mol
Synonyms	5-[(4-Chlorophenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidin-4-one; 5-(4-Chlorobenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ol; 402570-41-6; 5-(p-Chlorobenzyl)-1H-pyrazolopyrimidin-4-one; 4(5H)-Pyrazolo[3,4-d]pyrimidinone, 5-[(4-chlorophenyl)methyl]-; 5-(4-Chlorobenzyl)-4-hydroxypyrazolo[3,4-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 5-(4-Chlorobenzyl)-1H-Pyrazolo[3,4-D]Pyrimidin-4(5H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.