Description

5-Pyrimidinecarboxylicacid,1,2,3,4-Tetrahydro-4-(3-Hydroxyphenyl)-6-Methyl-2-Oxo-,Propylester(9Ci) is a high-purity, synthetically derived pyrimidine derivative, serving as a critical advanced intermediate for pharmaceutical research and development. Its complex molecular architecture, featuring a tetrahydro-4-(3-hydroxyphenyl)-6-methyl-2-oxo-pyrimidine core with a propyl ester group, makes it a valuable scaffold for constructing novel active pharmaceutical ingredients (APIs). This compound is essential for medicinal chemists and process development scientists working in central nervous system (CNS) drug discovery, enzyme inhibitor development, and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) conditions.
• Biochemical Research: Potential use as a reference standard or inhibitor in enzymatic assays and biochemical studies.
• Academic Research: Utilized in universities and research institutes for exploring new synthetic methodologies and heterocyclic chemistry.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.

Basic Information

Product Name	5-Pyrimidinecarboxylicacid,1,2,3,4-Tetrahydro-4-(3-Hydroxyphenyl)-6-Methyl-2-Oxo-,Propylester(9Ci)
CAS No.	402515-10-0
Molecular Formula	C15H18N2O4
Molecular Weight	290.32 g/mol
Synonyms	Propyl 1,2,3,4-tetrahydro-4-(3-hydroxyphenyl)-6-methyl-2-oxopyrimidine-5-carboxylate; 4-(3-Hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid propyl ester; 402515-10-0; 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-4-(3-hydroxyphenyl)-6-methyl-2-oxo-, propyl ester; Propyl 4-(3-hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
EINECS	Contact for details

Quality Control

Our 5-Pyrimidinecarboxylicacid,1,2,3,4-Tetrahydro-4-(3-Hydroxyphenyl)-6-Methyl-2-Oxo-,Propylester(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC purity analysis, NMR and MS structural confirmation, and residual solvent screening, to ensure it meets the stringent requirements for pharmaceutical R&D. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.