Description

5-Pyrimidinecarboxylicacid,1,2,3,4-Tetrahydro-6-Methyl-4-(5-Methyl-2-Thienyl)-2-Oxo-,Ethylester(9Ci) CAS NO 402514-67-4 is a specialized heterocyclic organic compound that serves as a critical building block in advanced chemical synthesis. Its unique molecular architecture, featuring fused pyrimidine and thiophene rings, makes it a valuable intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This high-purity intermediate is primarily sought by research and development teams in the pharmaceutical, agrochemical, and fine chemical sectors for creating compounds with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Research: Building block for developing new generation pesticides and herbicides with specific modes of action.
• Material Science: Used in the research of organic semiconductors and advanced polymers due to its conjugated system.
• Chemical Biology Probes: Serves as a core structure for designing molecular probes and enzyme inhibitors in biochemical research.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule development.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	5-Pyrimidinecarboxylicacid,1,2,3,4-Tetrahydro-6-Methyl-4-(5-Methyl-2-Thienyl)-2-Oxo-,Ethylester(9Ci)
CAS No.	402514-67-4
Molecular Formula	C13H16N2O3S
Molecular Weight	280.34 g/mol
Synonyms	Ethyl 1,2,3,4-tetrahydro-6-methyl-4-(5-methyl-2-thienyl)-2-oxo-5-pyrimidinecarboxylate; 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-6-methyl-4-(5-methyl-2-thienyl)-2-oxo-, ethyl ester; 402514-67-4; Ethyl 4-(5-methylthiophen-2-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate; 4-(5-Methyl-2-thienyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our production of 5-Pyrimidinecarboxylicacid,1,2,3,4-Tetrahydro-6-Methyl-4-(5-Methyl-2-Thienyl)-2-Oxo-,Ethylester(9Ci) adheres to a stringent quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements, supporting development under cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.