Description

n-(1-Oxo-5Z,8Z,11Z,14Z-Eicosatetraenyl)-L-Alanine is a specialized eicosanoid derivative and a synthetic analog of arachidonic acid metabolites. This compound is of significant value in biochemical research as a key intermediate and reference standard for studying lipid signaling pathways, enzyme inhibition, and receptor interactions. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and analytical laboratories focused on inflammation, immunology, and metabolic disease research.

Application

• Biochemical Research Intermediate: Serves as a critical building block for the synthesis of more complex eicosanoid analogs and labeled tracers.
• Enzyme Inhibition Studies: Used as a substrate or inhibitor in assays targeting enzymes like lipoxygenases (LOX) and cyclooxygenases (COX).
• Reference Standard: Employed as a high-purity analytical standard for method development and quantification in LC-MS or HPLC analyses.
• Cell Signaling Research: Applied in studies investigating the role of oxidized fatty acid derivatives in cellular communication and inflammatory responses.
• Drug Discovery: Acts as a pharmacophore or starting material in medicinal chemistry programs aimed at developing novel anti-inflammatory agents.
• Metabolite Synthesis: Used to prepare specific metabolites for use in metabolic pathway mapping and biomarker identification.

Basic Information

Product Name	n-(1-Oxo-5Z,8Z,11Z,14Z-Eicosatetraenyl)-L-Alanine
CAS No.	401941-73-9
Molecular Formula	C₂₃H₃₇NO₃
Molecular Weight	375.55 g/mol
Synonyms	N-(1-Oxo-5Z,8Z,11Z,14Z-eicosatetraenyl)-L-alanine; L-Alanine, N-[(5Z,8Z,11Z,14Z)-1-oxo-5,8,11,14-eicosatetraenyl]-; Arachidonoyl Alanine derivative; 5Z,8Z,11Z,14Z-Eicosatetraenoyl-L-alanine; Oxo-eicosatetraenoyl alanine; EET-Alanine conjugate; AA-Ala analog
EINECS	Contact for details

Quality Control

Our n-(1-Oxo-5Z,8Z,11Z,14Z-Eicosatetraenyl)-L-Alanine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC purity assay, identity confirmation by NMR and mass spectrometry, and impurity profiling to ensure high batch-to-batch consistency and reliability for sensitive research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.