Description

5-Pyrimidinecarboxylicacid,1,2,3,4-Tetrahydro-2-Oxo-4-Phenyl-6-Propyl-,Ethylester(9Ci) CAS NO 401648-34-8 is a specialized heterocyclic building block belonging to the class of dihydropyrimidinone derivatives. This compound is valued for its complex molecular architecture, which serves as a critical scaffold in advanced organic synthesis and pharmaceutical research. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, cardiovascular diseases, or possessing anti-inflammatory properties.
• Agrochemical Research: Used as a core structure for developing new herbicides, fungicides, or insecticides with novel modes of action.
• Chemical Biology Probe: Serves as a scaffold for creating tool compounds to study enzyme function or protein-protein interactions in biological systems.
• Material Science: Potential building block for advanced organic materials, such as ligands for catalysis or components in organic electronics, due to its rigid, conjugated structure.
• Academic & Contract Research: Essential for methodological development in organic chemistry, including studies on asymmetric synthesis, cyclization reactions, and heterocycle functionalization.
• Custom Synthesis & Scale-Up: Supplied for custom manufacturing projects requiring this specific dihydropyrimidinone derivative for pilot-scale or commercial production.

Basic Information

Product Name	5-Pyrimidinecarboxylicacid,1,2,3,4-Tetrahydro-2-Oxo-4-Phenyl-6-Propyl-,Ethylester(9Ci)
CAS No.	401648-34-8
Molecular Formula	C₁₆H₂₀N₂O₃
Molecular Weight	288.34 g/mol
Synonyms	Ethyl 1,2,3,4-tetrahydro-2-oxo-4-phenyl-6-propylpyrimidine-5-carboxylate; 4-Phenyl-6-propyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid ethyl ester; 5-Carboethoxy-4-phenyl-6-propyl-3,4-dihydro-2(1H)-pyrimidinone; 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-2-oxo-4-phenyl-6-propyl-, ethyl ester; 401648-34-8; Dihydropyrimidinone derivative; Biginelli reaction product derivative.
EINECS	Contact for details

Quality Control

Our 5-Pyrimidinecarboxylicacid,1,2,3,4-Tetrahydro-2-Oxo-4-Phenyl-6-Propyl-,Ethylester(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to ensure the material meets your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to protect the contents from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.