Description

3'-Trifluoromethyl-Biphenyl-3-Ylamine is a high-purity aromatic amine derivative featuring a biphenyl core substituted with a trifluoromethyl group. This compound matters as a versatile and critical building block in advanced organic synthesis, prized for its ability to introduce both aromatic amine and electron-withdrawing trifluoromethyl functionalities into target molecules. It is primarily needed by R&D and production chemists in the pharmaceutical and agrochemical industries for the development of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and production of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science: Serves as a monomer or precursor in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research: Employed in academic and industrial laboratories for method development, catalysis studies, and the creation of compound libraries for screening.
• Dye and Pigment Industry: Acts as an intermediate in the synthesis of complex organic dyes and pigments.

Basic Information

Product Name	3'-Trifluoromethyl-Biphenyl-3-Ylamine
CAS No.	400749-02-2
Molecular Formula	C13H10F3N
Molecular Weight	237.22 g/mol
Synonyms	[3-(3-Trifluoromethylphenyl)phenyl]amine; 3'-Trifluoromethyl-[1,1'-biphenyl]-3-amine; 3-Amino-3'-trifluoromethylbiphenyl; 3-(3-Aminophenyl)benzotrifluoride; Biphenyl-3-ylamine, 3'-trifluoromethyl-; 3'-Trifluoromethylbiphenyl-3-amine; 3'-Trifluoromethyl-3-aminobiphenyl
EINECS	Contact for details

Quality Control

Our 3'-Trifluoromethyl-Biphenyl-3-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.