Description

2'-(Trifluoromethyl)-Biphenyl-3-Amine CAS NO 400744-68-5 is a high-purity aromatic amine derivative featuring a biphenyl core substituted with a trifluoromethyl group. This compound serves as a critical pharmaceutical intermediate and advanced organic building block for the synthesis of complex molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and inflammation.
• Agrochemical Synthesis: Building block for developing novel herbicides and fungicides, leveraging the stability imparted by the trifluoromethyl group.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis in fine chemical manufacturing.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced polymers and organic electronic materials.
• Life Sciences & Diagnostics: Intermediate for fluorescent probes and other diagnostic reagents used in biochemical assays.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client-specific research programs.

Basic Information

Product Name	2'-(Trifluoromethyl)-Biphenyl-3-Amine
CAS No.	400744-68-5
Molecular Formula	C13H10F3N
Molecular Weight	237.22 g/mol
Synonyms	[1,1'-Biphenyl]-3-amine, 2'-(trifluoromethyl)-; 2'-(Trifluoromethyl)[1,1'-biphenyl]-3-amine; 3-Amino-2'-(trifluoromethyl)biphenyl; 2-(Trifluoromethyl)biphenyl-3-amine; 2'-Trifluoromethylbiphenyl-3-ylamine; Biphenyl-3-amine, 2'-trifluoromethyl-; 2'-(Trifluoromethyl)-3-aminobiphenyl
EINECS	Contact for details

Quality Control

Every batch of 2'-(Trifluoromethyl)-Biphenyl-3-Amine is produced and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.