Description

Verdamicin is a potent aminoglycoside antibiotic belonging to the gentamicin complex. This compound is valued for its broad-spectrum bactericidal activity, particularly against Gram-negative bacteria. It is a critical active pharmaceutical ingredient (API) and intermediate for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing anti-infective therapies.

Application

• Primary use as an Active Pharmaceutical Ingredient (API) in the formulation of injectable antibiotic preparations.
• Key intermediate in the synthesis of novel aminoglycoside derivatives for pharmaceutical research and development.
• Reference standard for quality control and analytical testing in pharmaceutical manufacturing and regulatory compliance.
• Essential component in microbiological research for studying bacterial resistance mechanisms and antibiotic efficacy.
• Used in the preparation of veterinary medicinal products for treating bacterial infections in animals.

Basic Information

Product Name	Verdamicin
CAS No.	49863-48-1
Molecular Formula	C20H41N5O7
Molecular Weight	463.57 g/mol
Synonyms	Verdamicin; Antibiotic G 418; Geneticin; G418 Sulfate (common salt form); 2-Deoxy-4-O-(2,6-diamino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl)-5-O-[3-O-(2,6-diamino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl)-β-D-ribofuranosyl]-D-streptamine; Gentamicin X2; Component of Gentamicin Complex.
EINECS	256-485-8

Quality Control

Our Verdamicin is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC, to ensure it meets stringent pharmaceutical-grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with relevant guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Bacterial Endotoxins	< 1.0 EU/mg (where applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.