Description

3,5-Bis(Trifluoromethyl)-n-Ethylaniline is a high-value fluorinated aromatic amine building block, distinguished by its two electron-withdrawing trifluoromethyl groups. This unique structure imparts exceptional chemical stability and lipophilicity, making it a critical intermediate for advanced synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl groups improve biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a backbone for creating specialized ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials due to its ability to modify electronic properties.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3,5-Bis(Trifluoromethyl)-n-Ethylaniline
CAS No.	49850-16-0
Molecular Formula	C11H9F6N
Molecular Weight	269.19 g/mol
Synonyms	N-Ethyl-3,5-bis(trifluoromethyl)aniline; 3,5-Bis(trifluoromethyl)-N-ethylaniline; 3,5-Bis(trifluoromethyl)-N-ethylbenzenamine; N-Ethyl-α,α,α,α',α',α'-hexafluoro-3,5-xylidine; 1-Ethylamino-3,5-bis(trifluoromethyl)benzene; Benzenamine, N-ethyl-3,5-bis(trifluoromethyl)-; 49850-16-0
EINECS	Contact for details

Quality Control

Our production of 3,5-Bis(Trifluoromethyl)-n-Ethylaniline adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.