Description

2,4-Dichloro-5-Nitropyrimidine is a versatile and highly functionalized heterocyclic building block, primarily valued for its dual reactive sites which enable selective and sequential chemical modifications. This compound is a critical intermediate in the synthesis of complex molecules, particularly within the pharmaceutical and agrochemical sectors. It is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), nucleoside analogs, and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of antiviral, anticancer, and antibacterial agents, particularly for constructing pyrimidine-based nucleoside analogs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its nitropyrimidine core.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Potential building block for advanced organic materials, including ligands for catalysts and components in organic electronics.
• Dye & Pigment Industry: Intermediate in the production of specialized dyes and pigments due to its nitro and chloro substituents.

Basic Information

Product Name	2,4-Dichloro-5-Nitropyrimidine
CAS No.	49845-33-2
Molecular Formula	C4H2Cl2N3O2
Molecular Weight	193.98 g/mol
Synonyms	5-Nitro-2,4-dichloropyrimidine; 2,4-Dichloro-5-nitropyrimidine; 2,4-Dichloro-5-nitro-pyrimidine; Pyrimidine, 2,4-dichloro-5-nitro-; 5-Nitro-2,4-dichloro-1,3-diazine; 49845-33-2 (CAS)
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-5-Nitropyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements of our global clientele. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. This material is moisture-sensitive; ensure containers are kept tightly sealed to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.