Description

2-(2-Methoxy-Ethoxy)-5-Trifluoromethyl-Phenylamine is a specialized aromatic amine derivative featuring a trifluoromethyl group and a methoxyethoxy side chain, offering unique electronic and steric properties for advanced synthesis. This compound serves as a critical high-value building block in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorine chemistry for enhanced bioactivity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the trifluoromethyl group improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials due to its aromatic amine core and tailored substituents.
• Polymer & Resin Modifier: Incorporated to impart specific properties like solubility, thermal stability, or reactivity in specialty polymer chains.
• Organic Synthesis & Catalysis: Employed as a ligand or a sophisticated reagent in cross-coupling reactions and other catalytic processes.
• Research & Development: Essential for academic and industrial research exploring new chemical entities and structure-activity relationships (SAR).

Basic Information

Product Name	2-(2-Methoxy-Ethoxy)-5-Trifluoromethyl-Phenylamine
CAS No.	49750-74-5
Molecular Formula	C10H12F3NO2
Molecular Weight	235.20 g/mol
Synonyms	5-(Trifluoromethyl)-2-(2-methoxyethoxy)aniline; 2-(2-Methoxyethoxy)-5-(trifluoromethyl)aniline; 2-(2-Methoxyethoxy)-α,α,α-trifluoro-p-toluidine; 2-Amino-4-(trifluoromethyl)phenyl 2-methoxyethyl ether; 2-Methoxyethoxy-5-trifluoromethylphenylamine; 5-Trifluoromethyl-2-(2-methoxyethoxy)phenylamine; 49750-74-5; 2-(2-Methoxyethoxy)-5-trifluoromethylbenzenamine
EINECS	Contact for details

Quality Control

Our 2-(2-Methoxy-Ethoxy)-5-Trifluoromethyl-Phenylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Light yellow to brown liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.