Description

Dihydropteroyl Hexaglutamate CAS NO 49637-65-2 is a high-purity folate derivative and a key biochemical intermediate in the study of folate metabolism and enzymatic pathways. Its significance lies in its role as a precursor and substrate for critical biochemical research, enabling advancements in nutritional science and pharmaceutical development. This compound is essential for research institutions, pharmaceutical R&D departments, and manufacturers of high-grade biochemical reagents and reference standards.

Application

• Biochemical Research: Serves as a critical substrate and intermediate in enzymatic studies of folate metabolism and one-carbon transfer reactions.
• Pharmaceutical Development: Used as a reference standard and a key starting material in the synthesis and research of novel therapeutic agents targeting folate-dependent pathways.
• Nutritional Science: Employed in advanced research to understand the bioavailability, metabolism, and functional roles of complex folate vitamers.
• Enzyme Assay & Diagnostics: Acts as a specific substrate for the assay and characterization of dihydrofolate reductase (DHFR) and other folate-converting enzymes.
• High-Purity Reagent Manufacturing: Supplied to producers of cell culture media, diagnostic kits, and specialized biochemical reagents requiring defined folate sources.
• Academic Research: Utilized in university and institutional labs for metabolic pathway analysis, cancer research, and studies in developmental biology.

Basic Information

Product Name	Dihydropteroyl Hexaglutamate
CAS No.	49637-65-2
Molecular Formula	C₄₅H₅₈N₁₂O₂₂
Molecular Weight	1123.02 g/mol
Synonyms	DHPTGlu6; Dihydrofolate Heptaglutamate; Dihydroperoylhexaglutamate; Dihydropteroylpolyglutamate; 7,8-Dihydropteroyl-γ-hexaglutamate; NSC 113928; Folate Derivative Intermediate; H4PteGlu6
EINECS	Contact for details

Quality Control

Our Dihydropteroyl Hexaglutamate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring full traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC/UV)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.