Description

D-Cyclopropylglycine is a non-proteinogenic amino acid derivative featuring a cyclopropyl side chain, offering unique conformational constraints. This high-purity chiral building block is essential for advanced pharmaceutical research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It serves as a critical intermediate for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries seeking to modulate peptide and small molecule properties.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, including protease inhibitors and receptor modulators.
• Peptidomimetics & Constrained Peptides: Used to introduce conformational rigidity into peptide backbones to enhance metabolic stability, bioavailability, and binding selectivity.
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, and plant growth regulators with improved efficacy.
• Biochemical Research: Utilized as a substrate or inhibitor in enzymatic studies to investigate reaction mechanisms and enzyme specificity.
• Ligand Synthesis for Catalysis: Employed in the preparation of chiral ligands for asymmetric synthesis and homogeneous catalysis.
• Diagnostic Agent Development: A potential precursor for labeled compounds used in medical imaging and diagnostic assays.

Basic Information

Product Name	D-Cyclopropylglycine
CAS No.	49607-01-4
Molecular Formula	C5H9NO2
Molecular Weight	115.13 g/mol
Synonyms	(R)-2-Amino-2-cyclopropylacetic acid; D-2-Cyclopropylglycine; (R)-2-Cyclopropylglycine; (R)-Aminocyclopropanecarboxylic acid; D-CPG; (R)-Cyclopropylglycine; (2R)-2-Amino-2-cyclopropylacetic acid; UNII-9K3B8T2Y3P
EINECS	256-400-5

Quality Control

Our D-Cyclopropylglycine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.