Description

Fazadinium Bromide is a non-depolarizing neuromuscular blocking agent belonging to the bis-quaternary ammonium compound class. This compound is of significant interest in pharmacological research and development due to its specific action on nicotinic acetylcholine receptors at the neuromuscular junction. It serves as a critical reference standard and intermediate for researchers and manufacturers in the pharmaceutical and life sciences sectors, particularly those focused on anesthesiology, muscle relaxants, and neuropharmacology.

Application

• Pharmacological Research: Primary use as a reference standard in studies of neuromuscular blockade and nicotinic receptor function.
• Drug Development: Key intermediate in the synthesis and development of novel neuromuscular blocking agents and related therapeutic compounds.
• Biochemical Assays: Utilized in in vitro assays to study receptor-ligand interactions and signal transduction pathways.
• Academic Research: Used in university and institutional labs for fundamental research in neurobiology and anesthesiology.
• Quality Control: Serves as an analytical standard for the identification and quantification of fazadinium bromide in pharmaceutical formulations.

Basic Information

Product Name	Fazadinium Bromide
CAS No.	49564-56-9
Molecular Formula	C28H40Br2N4O2
Molecular Weight	624.46 g/mol
Synonyms	Fazadon; AH 8165D; 1,1'-Azobis[3-methyl-2-phenyl-1H-imidazo[1,2-a]pyridinium] dibromide; 3-Methyl-2-phenyl-1-(3-methyl-2-phenylimidazo[1,2-a]pyridin-1-ium-1-yl)imidazo[1,2-a]pyridin-1-ium dibromide; AH-8165D; Fazadinium Bromide Dihydrate (common form)
EINECS	Contact for details

Quality Control

Our Fazadinium Bromide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling. A Certificate of Analysis (COA) detailing the specific results for purity (typically by HPLC), residual solvents, and other critical parameters is provided with every shipment to guarantee traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.