Description

6-Ethyl-5-[4-(Trifluoromethoxy)Phenyl]-2,4-Pyrimidinediamine is a high-purity, functionalized pyrimidine derivative of significant interest in advanced organic synthesis. This compound matters as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, offering a unique trifluoromethoxy-phenyl scaffold. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used as a core scaffold for developing new generation pesticides and herbicides, leveraging the stability imparted by the trifluoromethoxy group.
• Chemical Biology Probe: Employed in academic and industrial research to study enzyme inhibition and protein-ligand interactions due to its diamine functionality.
• Material Science Precursor: Potential use in the synthesis of specialized ligands for catalysis or functional organic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring this specific heterocyclic structure.

Basic Information

Product Name	6-Ethyl-5-[4-(Trifluoromethoxy)Phenyl]-2,4-Pyrimidinediamine
CAS No.	49561-95-7
Molecular Formula	C13H13F3N4O
Molecular Weight	298.27 g/mol
Synonyms	5-(4-(Trifluoromethoxy)phenyl)-6-ethylpyrimidine-2,4-diamine; 2,4-Pyrimidinediamine, 6-ethyl-5-[4-(trifluoromethoxy)phenyl]-; 6-Ethyl-5-(4-trifluoromethoxyphenyl)pyrimidine-2,4-diyldiamine; 49561-95-7; 6-Ethyl-5-(4-(trifluoromethoxy)phenyl)-2,4-pyrimidinediamine
EINECS	Contact for details

Quality Control

Our 6-Ethyl-5-[4-(Trifluoromethoxy)Phenyl]-2,4-Pyrimidinediamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.