Description

7-((3Ar,4R,6R,6Ar)-6-(Aminomethyl)-2,2-Dimethyltetrahydrofuro[3,4-D][1,3]Dioxol-4-Yl)-7H-Pyrrolo[2,3-D]Pyrimidin-4-Amine is a high-purity nucleoside analog intermediate of significant importance in modern pharmaceutical synthesis. This compound is valued for its role as a key building block in the development of novel antiviral and anticancer therapeutics. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the synthesis of nucleoside-based active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of nucleoside analog antiviral drugs.
• Antiviral Drug Research: Used in the R&D of novel therapeutics targeting viral polymerases and reverse transcriptases.
• Oncology Research: Serves as a precursor in the development of chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Research: Utilized in enzymatic studies and as a substrate or inhibitor in biochemical assays.
• Process Development: Employed in scaling up and optimizing synthetic routes for complex nucleoside derivatives under GMP conditions.
• Labeled Compound Synthesis: A starting material for the preparation of isotopically labeled (e.g., C13, N15) versions for metabolic and pharmacokinetic studies.

Basic Information

Product Name	7-((3Ar,4R,6R,6Ar)-6-(Aminomethyl)-2,2-Dimethyltetrahydrofuro[3,4-D][1,3]Dioxol-4-Yl)-7H-Pyrrolo[2,3-D]Pyrimidin-4-Amine
CAS No.	49554-54-3
Molecular Formula	C15H19N5O3
Molecular Weight	317.35 g/mol
Synonyms	4-Amino-7-((3aR,4R,6R,6aR)-6-(aminomethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-7H-pyrrolo[2,3-d]pyrimidine; 7-((3aR,4R,6R,6aR)-6-(Aminomethyl)-2,2-dimethyltetrahydro-4H-furo[3,4-d][1,3]dioxol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine; 7-(6-Aminomethyl-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine; Nucleoside Analog Intermediate; Pyrrolo[2,3-d]pyrimidine nucleoside derivative.
EINECS	Contact for details

Quality Control

Our 7-((3Ar,4R,6R,6Ar)-6-(Aminomethyl)-2,2-Dimethyltetrahydrofuro[3,4-D][1,3]Dioxol-4-Yl)-7H-Pyrrolo[2,3-D]Pyrimidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.