Description

Pyr-His-Trp-Ser-Tyr-Gly-Leu-Gln-Pro-Gly-Nh2 is a synthetic decapeptide amide, also known as Gonadorelin, which acts as a potent agonist of the gonadotropin-releasing hormone (GnRH) receptor. This compound is of significant interest for its role in stimulating the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland. It is primarily utilized in pharmaceutical research and development, veterinary medicine, and diagnostic applications within the life sciences sector.

Application

• Pharmaceutical Research & Development: As a reference standard and active ingredient in the development of hormone-related therapies and diagnostic kits.
• Veterinary Medicine: Used in fertility treatments and reproductive management for livestock and companion animals.
• Endocrinology Studies: A critical tool for in vitro and in vivo research into the hypothalamic-pituitary-gonadal axis and hormone regulation.
• Diagnostic Manufacturing: Serves as a key component in the production of immunoassays and diagnostic reagents for measuring gonadotropin levels.
• Biochemical Synthesis: Used as a building block or intermediate in the synthesis of more complex peptide conjugates or analogs.
• Academic & Institutional Research: Employed in university and institutional labs for fundamental studies in physiology and peptide chemistry.

Basic Information

Product Name	Pyr-His-Trp-Ser-Tyr-Gly-Leu-Gln-Pro-Gly-Nh2
CAS No.	47922-48-5
Molecular Formula	C55H75N17O13
Molecular Weight	1182.3 g/mol
Synonyms	Gonadorelin; GnRH; LHRH; Luteinizing Hormone-Releasing Hormone; Gonadotropin-Releasing Hormone; Factrel; Gonadoliberin; Pyroglutamyl-histidyl-tryptophyl-seryl-tyrosyl-glycyl-leucyl-glutaminyl-prolyl-glycinamide; LH/FSH-RH; Cystorelin; Luliberin
EINECS	Contact for details

Quality Control

Our Pyr-His-Trp-Ser-Tyr-Gly-Leu-Gln-Pro-Gly-Nh2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for residual solvents and related substances. A Certificate of Analysis (COA) detailing purity, assay, and specific tests is provided with every shipment to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This hygroscopic (moisture-sensitive) material should be kept in a cool, dry place and allowed to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Assay (HPLC)	97.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.