Description

Cholecystokinin Octapeptide (2-8) (Desulfated) is a synthetic bioactive peptide fragment derived from the endogenous hormone cholecystokinin. This compound is a critical research tool for studying the structure-activity relationships and physiological roles of CCK, particularly in the central nervous system and gastrointestinal tract. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on neurobiology, endocrinology, and drug discovery.

Application

• Neuroscientific Research: Used as a reference standard and active agent to investigate the role of CCK receptors in anxiety, satiety, and nociception.
• Pharmacological Studies: Serves as a key intermediate or analog in the development of novel CCK receptor agonists or antagonists for therapeutic applications.
• Biochemical Assay Development: Employed in the calibration and validation of immunoassays (ELISA, RIA) and receptor binding assays targeting the CCK system.
• Academic & Clinical Research: Facilitates fundamental studies on peptide hormone metabolism, signal transduction pathways, and gut-brain axis communication.
• Reference Standard: Provides a high-purity standard for analytical methods, including HPLC and mass spectrometry, for quality control in peptide synthesis.

Basic Information

Product Name	Cholecystokinin Octapeptide (2-8) (Desulfated)
CAS No.	47910-79-2
Molecular Formula	C₄₉H₆₂N₁₀O₁₃S
Molecular Weight	1031.1 g/mol
Synonyms	CCK-8 (desulfated); Sincalide (desulfated analog); Cholecystokinin (26-33), desulfated; Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2 (desulfated); CCK Octapeptide, Desulfated; H-Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH2; CCK-8us; Desulfated Sincalide
EINECS	Contact for details

Quality Control

Our Cholecystokinin Octapeptide (2-8) (Desulfated) is manufactured under strict quality systems. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the stringent requirements for research-grade bioactive peptides. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), peptide content, amino acid analysis, and mass spectrometry (MS) data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.