Description

Z-D-Glu-Ome is a protected amino acid derivative widely used as a key chiral building block in organic synthesis. This compound is essential for the controlled construction of peptides and other complex molecules, offering high stereochemical purity and reactivity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and fine chemicals.

Application

• Peptide Synthesis: As a protected glutamic acid derivative for the solid-phase and solution-phase synthesis of biologically active peptides.
• Pharmaceutical Intermediates: A crucial chiral precursor in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs.
• Bioconjugation: Used in the preparation of peptide-drug conjugates and other targeted delivery systems.
• Chemical Biology Research: Employed as a tool compound for studying enzyme mechanisms and protein-protein interactions.
• Ligand Development: Serves as a building block for creating custom ligands and catalysts in asymmetric synthesis.
• Fine Chemical Production: A valuable intermediate in the manufacture of specialty chemicals and advanced materials.

Basic Information

Product Name	Z-D-Glu-Ome
CAS No.	47087-37-6
Molecular Formula	C14H17NO6
Molecular Weight	295.29 g/mol
Synonyms	N-Carbobenzoxy-D-glutamic acid α-methyl ester; Z-D-Glutamic acid 1-methyl ester; (R)-2-((Benzyloxy)carbonylamino)pentanedioic acid 1-methyl ester; Nα-Cbz-D-glutamic acid α-methyl ester; N-Cbz-D-Glu-OMe; CBZ-D-Glutamic Acid α-Methyl Ester; Benzyloxycarbonyl-D-glutamic acid α-methyl ester
EINECS	Contact for details

Quality Control

Our Z-D-Glu-Ome is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC chromatograms for purity and optical rotation for chiral identity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	-10.0° to -12.0° (c=1 in DMF)
Loss on Drying	≤0.5%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.