Description

γ-Glutamylhistamine is a naturally occurring dipeptide derivative formed from the conjugation of glutamic acid and histamine. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a potential biomarker and its involvement in histamine metabolism pathways. It is primarily utilized by researchers and developers in the life sciences sector for analytical standards, metabolic studies, and the development of diagnostic assays. The product is supplied under stringent quality control to ensure reliability for sensitive applications.

Application

• Biochemical Research Standard: Used as a high-purity reference standard for analytical method development and validation in chromatography (HPLC, LC-MS).
• Metabolite Studies: Employed in research to investigate histamine-related metabolic pathways, enzymatic activity, and biomarker discovery.
• Diagnostic Development: Serves as a critical component in the development and calibration of diagnostic kits and assays for detecting histamine metabolites.
• Pharmaceutical Intermediates: Potential use as a building block or intermediate in the synthesis of novel pharmaceutical compounds targeting neurological or inflammatory conditions.
• Food & Beverage Analysis: Applied in research laboratories for analyzing histamine and its derivatives in food products for safety and quality control.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in biochemistry, physiology, and pharmacology.

Basic Information

Product Name	γ-Glutamylhistamine
CAS No.	46843-88-3
Molecular Formula	C11H16N4O4
Molecular Weight	268.27 g/mol
Synonyms	L-γ-Glutamylhistamine; γ-Glutamylhistamine; N-(γ-L-Glutamyl)histamine; Histamine γ-glutamate; Glutamyl-histamine; GLH; 5-L-Glutamylhistamine; (2S)-2-Amino-5-[[2-(1H-imidazol-4-yl)ethyl]amino]-5-oxopentanoic acid
EINECS	Contact for details

Quality Control

Our γ-Glutamylhistamine is produced and tested under a rigorous quality management system to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. While typically supplied as a research-grade material, production can adhere to cGMP guidelines for advanced applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.