Description

2,6-Bis(Trifluoromethyl)Phenol is a high-value fluorinated phenolic compound characterized by its two electron-withdrawing trifluoromethyl groups, which impart unique chemical reactivity and stability. This compound serves as a critical advanced intermediate for synthesizing sophisticated materials and active ingredients, enabling enhanced performance in demanding applications. It is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty polymer sectors seeking to incorporate fluorine chemistry for improved product properties.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the trifluoromethyl groups contribute to increased lipophilicity and biological activity.
• Ligand and Catalyst Precursor: Serves as a starting material for creating specialized ligands in transition metal catalysis, useful in fine chemical and asymmetric synthesis.
• Polymer and Material Science: Incorporated into high-performance polymers, resins, and coatings to improve chemical resistance, thermal stability, and surface properties.
• Organic Electronic Materials: Investigated as a component in the development of organic semiconductors and electron-transport materials due to its electronic characteristics.
• Research & Development: A valuable reagent for academic and industrial R&D in fluorine chemistry, medicinal chemistry, and material science.

Basic Information

Product Name	2,6-Bis(Trifluoromethyl)Phenol
CAS No.	46377-35-9
Molecular Formula	C8H4F6O
Molecular Weight	230.11 g/mol
Synonyms	2,6-Bis(trifluoromethyl)phenol; 2,6-Di(trifluoromethyl)phenol; Phenol, 2,6-bis(trifluoromethyl)-; α,α,α,α',α',α'-Hexafluoro-2,6-xylenol; 2-Hydroxy-1,3-bis(trifluoromethyl)benzene; 2,6-BTFMP; HQ-2,6-BTFM
EINECS	Contact for details

Quality Control

Our 2,6-Bis(Trifluoromethyl)Phenol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly sealed due to potential moisture sensitivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	40-44 °C
Loss on Drying	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.