Description

(Deamino-Cys1,Val4,D-Arg8)-Vasopressin is a synthetic analogue of the neurohypophysial hormone vasopressin, specifically engineered to exhibit potent and selective antidiuretic activity. This modification enhances its metabolic stability and receptor specificity, making it a critical research tool and active pharmaceutical ingredient (API) for developing therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on endocrinology, renal physiology, and the development of treatments for conditions like diabetes insipidus.

Application

• Pharmaceutical Research & Development: As a reference standard and key intermediate in the synthesis of novel antidiuretic drugs.
• Biochemical Studies: For investigating vasopressin receptor (V2) binding, signal transduction pathways, and cellular responses.
• Preclinical Studies: Utilized in animal models to study renal water reabsorption, electrolyte balance, and the pathophysiology of water balance disorders.
• API Manufacturing: Serves as the active ingredient in the formulation of investigational medicinal products targeting antidiuretic hormone deficiency.
• Diagnostic Aid Development: Potential use in the development of diagnostic assays for renal function and endocrine disorders.

Basic Information

Product Name	(Deamino-Cys1,Val4,D-Arg8)-Vasopressin
CAS No.	43157-23-9
Molecular Formula	C46H65N13O12S2
Molecular Weight	1032.2 g/mol
Synonyms	Desmopressin Impurity C; dDAVP Impurity C; 1-Desamino-8-D-arginine Vasopressin (Deamino-Cys1,Val4,D-Arg8)-; (1-β-Mercaptopropionic acid, 4-valine, 8-D-arginine)vasopressin; Deamino Val4-D-Arg8-Vasopressin; [1-Deamino, 4-Valine, 8-D-Arginine]Vasopressin; ADH Analogue; Antidiuretic Hormone Analogue
EINECS	Contact for details

Quality Control

Our (Deamino-Cys1,Val4,D-Arg8)-Vasopressin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for related substances and residual solvents, ensuring it meets exacting standards for research and development use. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.