Description

Ethyl 3-Bromo-7-Hydroxypyrazolo[1,5-A]Pyrimidine-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyrazolopyrimidine heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing next-generation small-molecule drugs and specialty chemicals.

Application

This specialized intermediate serves as a critical precursor in various synthetic pathways. Its primary applications include:

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides due to its bioactive heterocyclic core.
• Chemical Synthesis: Serves as a versatile substrate for further functionalization, enabling the creation of diverse compound libraries for screening.
• Academic & R&D: Employed in university and institutional research for studying heterocyclic chemistry and reaction mechanisms.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials or ligands for catalytic systems.

Basic Information

Product Name	Ethyl 3-Bromo-7-Hydroxypyrazolo[1,5-A]Pyrimidine-6-Carboxylate
CAS No.	43024-63-1
Molecular Formula	C9H8BrN3O3
Molecular Weight	286.08 g/mol
Synonyms	Ethyl 3-bromo-7-hydroxypyrazolo[1,5-a]pyrimidine-6-carboxylate; 3-Bromo-7-hydroxy-6-(ethoxycarbonyl)pyrazolo[1,5-a]pyrimidine; 6-Carbethoxy-3-bromo-7-hydroxypyrazolo[1,5-a]pyrimidine; Ethyl 3-bromo-7-oxo-6,7-dihydropyrazolo[1,5-a]pyrimidine-6-carboxylate; 43024-63-1; Pyrazolo[1,5-a]pyrimidine-6-carboxylic acid, 3-bromo-7-hydroxy-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-Bromo-7-Hydroxypyrazolo[1,5-A]Pyrimidine-6-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.