Description

5,7-Dimethyl-3-Iodopyrazolo[1,5-A]Pyrimidine is a high-value iodinated heterocyclic building block with significant utility in advanced organic synthesis. Its core value lies in its role as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and R&D professionals in the pharmaceutical, agrochemical, and material science industries seeking to develop new active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other biological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive pyrazolopyrimidine core.
• Material Science: Serves as a building block for organic electronic materials, such as OLEDs and semiconductors, where its halogenated structure aids in tuning electronic properties.
• Chemical Biology: Employed in the creation of molecular probes and tags for studying biological processes and protein interactions.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig couplings.
• Library Synthesis: Used in high-throughput and combinatorial chemistry for generating diverse compound libraries for screening.

Basic Information

Product Name	5,7-Dimethyl-3-Iodopyrazolo[1,5-A]Pyrimidine
CAS No.	43024-26-6
Molecular Formula	C8H8IN3
Molecular Weight	273.08 g/mol
Synonyms	3-Iodo-5,7-dimethylpyrazolo[1,5-a]pyrimidine; 5,7-Dimethyl-3-iodo-1H-pyrazolo[1,5-a]pyrimidine; Pyrazolo[1,5-a]pyrimidine, 3-iodo-5,7-dimethyl-; 43024-26-6; 3-Iodo-5,7-dimethylpyrazolo[1,5-a]pyrimidine; 5,7-Dimethyl-3-iodopyrazolo[1,5-a]pyrimidine
EINECS	Contact for details

Quality Control

Our 5,7-Dimethyl-3-Iodopyrazolo[1,5-A]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.