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(2R,3S)-2-Amino-3-[[(2R)-2-Amino-2-Carboxyethyl]Thio]Butyric Acid CAS NO 42849-29-6


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CAS No.:42849-29-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(2R,3S)-2-Amino-3-[[(2R)-2-Amino-2-Carboxyethyl]Thio]Butyric Acid is a high-purity, stereochemically defined sulfur-containing amino acid derivative. This compound is critical for advanced pharmaceutical research and development, particularly in the synthesis of complex peptides and enzyme inhibitors. It serves as a key chiral building block for medicinal chemists and biochemists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

  • Pharmaceutical Intermediate: A crucial chiral synthon for the development of novel therapeutic agents, including protease inhibitors and other enzyme-targeted drugs.
  • Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate specific thioether linkages and chiral centers into bioactive peptide sequences.
  • Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies to investigate sulfur metabolism and amino acid processing pathways.
  • Asymmetric Synthesis: Employed as a starting material or auxiliary in asymmetric catalytic reactions to construct complex molecules with high enantiomeric purity.
  • Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name (2R,3S)-2-Amino-3-[[(2R)-2-Amino-2-Carboxyethyl]Thio]Butyric Acid
CAS No. 42849-29-6
Molecular Formula C7H12N2O4S
Molecular Weight 220.25 g/mol
Synonyms L-Cystathionine; (2R,3S)-2-Amino-3-[(R)-2-Amino-2-carboxyethylthio]butyric Acid; (2R,3S)-Cystathionine; (2R,3S)-2-Amino-4-[(2R)-2-amino-2-carboxyethyl]thio]butanoic Acid; 3-[(2-Amino-2-carboxyethyl)thio]-2-aminobutanoic Acid; (2R,3S)-3-[[(2R)-2-Amino-2-carboxyethyl]thio]-2-aminobutanoic Acid
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Quality Control

Our (2R,3S)-2-Amino-3-[[(2R)-2-Amino-2-Carboxyethyl]Thio]Butyric Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, confirming identity, purity, and stereochemical integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent exposure to atmospheric moisture.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Chiral Purity (HPLC) ≥ 99.0% de
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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