Description

β-Methyllanthionine is a specialized, sulfur-containing amino acid derivative that serves as a key building block and research chemical. This compound is of significant interest for its role in the synthesis and study of complex bioactive peptides, particularly lanthipeptides. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and advanced chemical synthesis sectors for developing novel therapeutics and studying structure-activity relationships.

Application

• Pharmaceutical Research: Critical intermediate in the synthesis of lanthipeptides, a class of ribosomally synthesized and post-translationally modified peptides (RiPPs) with antibiotic and other bioactive properties.
• Bioconjugation & Peptide Engineering: Used to introduce specific thioether bridges into synthetic peptides, enhancing their stability, structural rigidity, and biological activity.
• Biochemical Studies: Serves as a standard or reference compound in analytical methods (HPLC, MS) for identifying and quantifying lanthionine derivatives in complex biological samples.
• Academic & Industrial R&D: Fundamental building block for investigating novel enzymatic pathways and developing new methodologies in peptide chemistry.
• Precursor for Specialty Chemicals: Used in the development of custom amino acid analogs and other high-value fine chemicals for specialized applications.

Basic Information

Product Name	β-Methyllanthionine
CAS No.	42849-28-5
Molecular Formula	C7H14N2O4S
Molecular Weight	222.26 g/mol
Synonyms	(2S,6R)-3-[(2R)-2-Amino-2-carboxyethyl]-6-methyl-1,4-thiomorpholine-2,5-dione; (2S,6R)-3-[(2R)-2-Amino-2-carboxyethyl]-6-methyl-1,4-thiomorpholine-2,5-dione; β-Methyllanthionine; L-β-Methyllanthionine; (2S,3S,6R)-2-Amino-3-[[(2R)-2-amino-2-carboxyethyl]thio]hexanoic acid; LanB amino acid derivative
EINECS	Contact for details

Quality Control

Our β-Methyllanthionine is produced under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, MS). We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality system is designed to support research and development applications where precise chemical structure and purity are paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% de
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.