Description

Gly-Pro 4-Methoxy-β-Naphthylamide is a specialized chromogenic peptide substrate used as a key reagent in enzymatic assays. This compound is critical for the detection and quantification of specific protease activities, particularly dipeptidyl peptidase IV (DPP-IV), in biochemical and pharmaceutical research. It is essential for researchers and quality control laboratories in the pharmaceutical, diagnostic, and life science sectors who require precise and reliable substrates for enzyme kinetics and inhibitor screening studies.

Application

• Enzymatic Substrate for DPP-IV (CD26): Primary reagent for the spectrophotometric or fluorometric assay of dipeptidyl peptidase IV activity.
• Biochemical Research: Used in kinetic studies, enzyme characterization, and mechanism-of-action research for proteases.
• Pharmaceutical Drug Discovery: High-throughput screening (HTS) of potential DPP-IV inhibitors for the development of therapeutics targeting type 2 diabetes and other conditions.
• Diagnostic Reagent Manufacturing: A key component in the formulation of diagnostic kits for clinical and research use.
• Cell Biology & Immunology: Assaying DPP-IV activity in cell cultures and tissue samples to study its role in immune regulation and cell signaling.
• Quality Control (QC) Testing: Used in QC laboratories to standardize and validate enzymatic assay procedures.

Basic Information

Product Name	Gly-Pro 4-Methoxy-β-Naphthylamide
CAS No.	42761-76-2
Molecular Formula	C18H21N3O3
Molecular Weight	327.38 g/mol
Synonyms	Glycyl-proline 4-methoxy-2-naphthylamide; Gly-Pro-4-MeO-β-NA; GP-4-MeO-βNA; DPP-IV Substrate; 4-Methoxy-2-naphthylamide-Gly-Pro; H-Gly-Pro-4-methoxy-2-naphthylamide; L-Glycyl-L-proline 4-methoxy-β-naphthylamide; Dipeptidyl Peptidase IV Chromogenic Substrate
EINECS	Contact for details

Quality Control

Our Gly-Pro 4-Methoxy-β-Naphthylamide is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant industry standards for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content	≤ 1.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.