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3β-(N,n-Diethylaminoacetyloxy)-14-Hydroxy-5β-Card-20(22)-Enolide CAS NO 42716-82-5


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CAS No.:42716-82-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3β-(N,n-Diethylaminoacetyloxy)-14-Hydroxy-5β-Card-20(22)-Enolide is a high-purity, synthetic cardiac glycoside derivative, a class of compounds known for their potent biological activity. This compound is critical for pharmaceutical research and development, particularly in the study of cardiac function and the synthesis of novel therapeutic agents. It serves as a key intermediate or reference standard for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require precise and reliable bioactive molecules.

Application

  • Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel cardiac glycoside-based drugs and prodrugs.
  • Biochemical Research: Used as a reference standard or active compound in studies investigating sodium-potassium ATPase (Na⁺/K⁺-ATPase) inhibition and cardiac cell signaling pathways.
  • Reference Standard: Employed in analytical laboratories for method development, validation, and quality control testing of related pharmaceutical products.
  • Medicinal Chemistry: Acts as a core scaffold for structure-activity relationship (SAR) studies to develop new therapeutic agents with optimized efficacy and safety profiles.
  • Academic Research: Utilized in university and institutional labs for pharmacological and toxicological studies related to heart failure and arrhythmias.

Basic Information

Product Name 3β-(N,n-Diethylaminoacetyloxy)-14-Hydroxy-5β-Card-20(22)-Enolide
CAS No. 42716-82-5
Molecular Formula C₃₁H₄₇NO₆
Molecular Weight 529.72 g/mol
Synonyms 14-Hydroxy-3β-(2-diethylaminoacetoxy)-5β-card-20(22)-enolide; 3β-(N,N-Diethylglycolamido)-14-hydroxy-5β-card-20(22)-enolide; Deslanoside Impurity; Cardiac Glycoside Derivative; 3β-(2-Diethylaminoacetoxy)-14-hydroxy-5β,14β-card-20(22)-enolide; Lanatoside C Related Compound
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Quality Control

Our 3β-(N,n-Diethylaminoacetyloxy)-14-Hydroxy-5β-Card-20(22)-Enolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets the stringent requirements for research and pharmaceutical development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere at 2-8°C to ensure maximum stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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