Description

n-(2-Pyridinylmethylene)-L-Val-L-Ile-L-Ala-L-Leu-L-Leu-L-Leu-Ome is a synthetic peptide derivative featuring a pyridinylmethylene group and a sequence of hydrophobic amino acids. This compound is of significant interest in advanced pharmaceutical research and development, particularly for its potential role as a protease inhibitor or as a specialized building block in medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of novel therapeutic agents, especially those targeting enzymatic pathways.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or lead compound in the synthesis of novel protease inhibitors and other bioactive peptides.
• Medicinal Chemistry: Used as a specialized scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic assays to study protease function and mechanism.
• Peptide Synthesis: Acts as a protected peptide fragment for use in solid-phase or solution-phase peptide synthesis campaigns.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic chemistry, peptide science, and drug design.

Basic Information

Product Name	n-(2-Pyridinylmethylene)-L-Val-L-Ile-L-Ala-L-Leu-L-Leu-L-Leu-Ome
CAS No.	42547-82-0
Molecular Formula	C41H68N8O7
Molecular Weight	785.03 g/mol
Synonyms	Pyridinylmethylene-Val-Ile-Ala-Leu-Leu-Leu-OMe; (S)-Methyl 2-((S)-2-((S)-2-((S)-2-((S)-2-((S)-2-((E)-((pyridin-2-yl)methylene)amino)-3-methylbutanamido)-3-methylpentanamido)propanamido)-4-methylpentanamido)-4-methylpentanamido)-4-methylpentanoate; L-Val-L-Ile-L-Ala-L-Leu-L-Leu-L-Leu-OMe Schiff Base; Peptide Inhibitor Intermediate; N-[(E)-Pyridin-2-ylmethylidene]valylisoleucylalanylleucylleucylleucine Methyl Ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of n-(2-Pyridinylmethylene)-L-Val-L-Ile-L-Ala-L-Leu-L-Leu-L-Leu-Ome is analyzed using advanced techniques like HPLC and NMR to confirm identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are available upon request to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.