Description

Boc-Leu-Oh Cs is a cesium salt derivative of the N-Boc-protected amino acid L-leucine, a crucial building block in peptide synthesis. This compound is specifically valued for its enhanced solubility in organic solvents compared to its free acid counterpart, facilitating more efficient coupling reactions. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for the solid-phase and solution-phase synthesis of complex peptides and peptidomimetics.

Application

• Peptide Synthesis: A key intermediate for the incorporation of leucine residues using standard Boc (tert-butyloxycarbonyl) chemistry protocols.
• Pharmaceutical Research: Used in the research and development of novel therapeutic peptides, including hormone analogs and enzyme inhibitors.
• Bioconjugation: Serves as a reagent for modifying biomolecules by introducing leucine-based linkers or functional groups.
• Combinatorial Chemistry: Employed in the generation of peptide libraries for drug discovery and screening applications.
• Academic Research: A standard reagent in university and institutional labs for studying peptide structure, function, and synthesis methodologies.
• API Intermediate: Acts as a critical raw material in the multi-step synthesis of Active Pharmaceutical Ingredients (APIs) that contain leucine.

Basic Information

Product Name	Boc-Leu-Oh Cs
CAS No.	42538-67-0
Molecular Formula	C11H20CsNO4
Molecular Weight	371.23 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-L-leucine cesium salt; Boc-L-leucine cesium salt; (S)-2-((tert-Butoxycarbonyl)amino)-4-methylpentanoic acid cesium salt; Cesium N-Boc-leucinate; Boc-Leu-OCs; BOC-Leu-OH Cs; N-Boc-L-leucine Cs salt; tert-Butyloxycarbonyl-L-leucine cesium salt
EINECS	Contact for details

Quality Control

Our Boc-Leu-Oh Cs is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. We provide full traceability and a Certificate of Analysis (COA) with every shipment, ensuring compliance with research and cGMP-grade material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.