Description

H-Gly-β-Ala-Gly-Oh is a synthetic tripeptide derivative, specifically a glycine-β-alanine-glycine sequence with a free carboxylic acid terminus. This compound serves as a crucial building block and model peptide in advanced biochemical research and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the fields of peptide synthesis, medicinal chemistry, and proteomics for studying peptide structure-activity relationships and developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the solid-phase and solution-phase synthesis of more complex therapeutic peptides and peptidomimetics.
• Biochemical Research: Used as a model compound in studies of peptide folding, stability, and interactions due to its simple yet representative structure.
• Protease Substrate Analog: Acts as a substrate or inhibitor analog in enzymatic assays to study the specificity and mechanism of proteolytic enzymes.
• Cosmetic Peptide Precursor: Employed in the development of bioactive peptides for cosmetic applications, such as skin-conditioning agents.
• Material Science: Investigated for the creation of peptide-based biomaterials and hydrogels, leveraging its self-assembly properties.
• Standards & Calibration: Provides a high-purity reference standard for analytical methods including HPLC and mass spectrometry in quality control laboratories.

Basic Information

Product Name	H-Gly-β-Ala-Gly-Oh
CAS No.	42538-54-5
Molecular Formula	C9H15N3O5
Molecular Weight	245.23 g/mol
Synonyms	Glycyl-β-alanylglycine; G-β-A-G-OH; H-Gly-β-Ala-Gly-OH; Gly-β-Ala-Gly; Tripeptide Gly-β-Ala-Gly; 2-[[2-[(2-Aminoacetyl)amino]propanoyl]amino]acetic acid; β-Alanyl-glycyl-glycine; (Glycine-β-alanine-glycine)
EINECS	Contact for details

Quality Control

Our H-Gly-β-Ala-Gly-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and cGMP-grade standards as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.